Nutrient exchange

Red blood cells are the oxygen carriers. As they travel away from the heart, they traverse smaller and smaller arteries, finally arriving at the collections of microscopic blood vessels, known as capillaries. Here, they exchange nutrients and oxygen for cellular waste products. The exchange of oxygen and nutrients between the red blood cells and the surrounding tissues occurs through a process called diffusion.

In diffusion, when capillaries contain a high concentration of oxygen and nutrients, while the surrounding tissues contain a lower concentration, oxygen and nutrients leave the capillaries and enters the tissues.

Conversely, when body tissues contain high concentrations of carbon dioxide and metabolic waste, while the capillaries contain a lower concentration, the waste products diffuse from the tissues into the capillaries, and from there are carried by the venous system back toward the heart.

The waste products are eventually eliminated from the bloodstream through the urinary and respiratory systems.

Review Date:4/5/2025
Reviewed By:Charles I. Schwartz, MD, FAAP, Clinical Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, General Pediatrician at PennCare for Kids, Phoenixville, PA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997-A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

The Agency for Health Care Administration (Agency) and this website do not claim the information on, or referred to by, this site is error free. This site may include links to websites of other government agencies or private groups. Our Agency and this website do not control such sites and are not responsible for their content. Reference to or links to any other group, product, service, or information does not mean our Agency or this website approves of that group, product, service, or information.

Additionally, while health information provided through this website may be a valuable resource for the public, it is not designed to offer medical advice. Talk with your doctor about medical care questions you may have.